12:03:38 (ESRI) Unable to re-open lock file (C:\flexlm\ESRI): Permission denied
12:03:38 (ESRI) IN: "ARC/INFO" <username>@hostname (SHUTDOWN)
12:03:45 (lmgrd) MULTIPLE "ESRI" servers running.
12:03:45 (lmgrd) Please kill, and run lmreread
12:03:45 (lmgrd)
12:03:45 (lmgrd) This error probably results from either:
12:03:45 (lmgrd) 1. Another copy of lmgrd running
12:03:45 (lmgrd) 2. A prior lmgrd was killed with "kill -9"
12:03:45 (lmgrd) (which would leave the vendor daemon running)
12:03:45 (lmgrd) To correct this, do a "ps -ax | grep ESRI"
12:03:45 (lmgrd) (or equivalent "ps" command)
12:03:45 (lmgrd) and kill the "ESRI" process
In order for the license manager to run, the vendor daemon must be able to establish an exclusive lock on the files in this folder.
This error can occur if any of the following are true:
Another ESRI vendor daemon is already running. For instance, in a command window. An attempt has been made to start the ESRI vendor daemon when it is already running or being used by another application.
These files are being used by antivirus software. When the antivirus software opens the files in the C:\FlexLM folder to scan them for viruses, the vendor daemon cannot exclusively access the files; the license manager shuts down. Norton Corporate Edition and McAffee antivirus software have been known to cause this error.
These files have been marked as Read Only. Antivirus software may mark these files as Read Only after a virus scan; this will also cause the above error. Go to the c:\FlexLM folder and right click on each of the files. Verify that they are not marked as Read Only or Archive. Restart your license manager.
Stop your license manager. Do not restart!
Stopping the license manager on Windows
Stopping the license manager on UNIX
Delete all the files in you C:\flexlm folder.
Restart your license manager. The files will automatically be recreated when the license manager restarts.
To permanently resolve this issue, you need to set your antivirus software to exclude the C:\Flexlm folder. This can typically be found in the antivirus software interface under Tools > Options > Exclusions (location will vary depending on the software and version).